Lavoltidine; Uses, Dosage, Side Effects, Interactions

Lavoltidine is a highly potent and selective H₂receptor antagonist which was under development & used as a treatment for gastroesophageal reflux disease but was discontinued due to the discovery that it produced gastric carcinoid tumors in rodents.

Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.

Mechanism of Lavoltidine

This product is under development.

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References

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