Multiple Myeloma (MM) is a fatal, malignant B-cell neoplasm characterized by uncontrolled, destructive growth of mutated plasma cells within the bone marrow (BM). Patients over age 65 are most commonly affected by this disease[rx] and, as indicated by its name, Read More …
Month: October 2020
MGUS – Causes, Symptoms, Diagnosis, Treatment
MGUS (Monoclonal Gammopathy of Undetermined Significance) is characterized by a serum M protein concentration of less than 30 g/L, fewer than 10% clonal plasma cells in the bone marrow, and the absence of end-organ damage that can be attributed to Read More …
Monoclonal Gammopathy of Undetermined Significance (MGUS)
Monoclonal Gammopathy of Undetermined Significance (MGUS) is characterized by a serum M protein concentration of less than 30 g/L, fewer than 10% clonal plasma cells in the bone marrow, and the absence of end-organ damage that can be attributed to Read More …
Waldenström Macroglobulinemia – Symptoms, Treatment
Waldenström Macroglobulinemia (WM) is a low-grade B-cell clonal disorder characterized by lymphoplasmacytic bone marrow involvement associated with monoclonal immunoglobulin M (IgM). Although WM remains to be an incurable disease with a heterogeneous clinical course, the recent discovery of mutations in Read More …
Lymphoplasmacytic Lymphoma – Causes, Symptpoms, Treatment
Lymphoplasmacytic Lymphoma (LPL) is a rare type of non-Hodgkin lymphoma that is characterized by infiltration of small B lymphocytes, plasmacytoid lymphocytes, and plasma cells. The condition most commonly affects the bone marrow, followed by lymph nodes and spleen, and, to Read More …
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