A fibroadenoma is a painless, unilateral, benign (non-cancerous) breast tumor that is a solid, not fluid-filled, lump. It occurs most commonly in women between the age of 14 to 35 years but can be found at any age. Fibroadenomas shrink after Read More …
Month: October 2020
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MALT Lymphoma – Causes, Symptoms, Treatment
MALT Lymphoma/Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) Lymphoma is a mature B-cell neoplasm that typically follows an indolent clinical course. Amyloid deposition associated with MALT lymphoma is uncommon. We describe the clinical and pathologic features of 20 Read More …
Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) lymphoma is a mature B-cell neoplasm that typically follows an indolent clinical course. Amyloid deposition associated with MALT lymphoma is uncommon. We describe the clinical and pathologic features of 20 cases Read More …
Monoclonal Immunoglobulin Deposition Disease (MIDD)
Monoclonal immunoglobulin deposition disease (MIDD) is a rare disease characterized by the deposition of monoclonal Ig molecules in basement membranes. In contrast to amyloidosis, the deposits in MIDD are nonfibrillar and Congo-red negative. MIDD includes three subtypes depending on the Read More …
Extramedullary Plasmacytoma – Causes, Symptoms, Treatment
Extramedullary Plasmacytoma is a rare tumor and accounts for 3-5% of all plasma cell neoplasms. Approximately 80% of them occur in the upper aerodigestive tract. Extramedullary plasmacytoma chiefly affects adults older than 65-years-old and there is a male preponderance of Read More …
Plasmacytoma – Causes, Symptoms, Diagnosis, Treatment
Plasmacytoma is a plasma cell dyscrasia in which a plasma cell tumour grows within soft tissue or within the axial skeleton. The International Myeloma Working Group lists three types: solitary plasmacytoma of bone (SPB); extramedullary plasmacytoma (EP), and multiple plasmacytomas that are either primary or recurrent.[rx] The most common of these is SPB, accounting Read More …
Solitary Plasmacytoma – Causes, Symptoms, Treatment
The Solitary Plasmacytoma (SP) is characterized by a localized accumulation of neoplastic monoclonal plasma cells without proof of a systemic plasma cell proliferative disorder. It is an infrequent form of plasma cell neoplasm and represents 5% to 10% of all Read More …
What Is Plasma Cell Myeloma? – Symptoms, Treatment
What Is Plasma Cell Myeloma?/Plasma Cell Myeloma is a neoplastic plasma cell disorder that usually presents after the fifth decade of life; it is rarely described in the younger population especially under 30 years of age. In approximately 2% of Read More …
Plasma Cell Myeloma – Causes, Symptoms, Treatment
Plasma Cell Myeloma is a neoplastic plasma cell disorder that usually presents after the fifth decade of life; it is rarely described in the younger population especially under 30 years of age. In approximately 2% of plasma cell myeloma, the Read More …
Plasmablastic Lymphoma – Causes, Symptoms, Treatment
Plasmablastic Lymphoma (PBL) is an uncommon but aggressive subtype of diffuse, large, B-cell lymphoma. The diagnosis of PBL is difficult because its features overlap with myeloma and lymphoma. The primary organs involved are usually the gastrointestinal system, lymph nodes, oral Read More …
Plasma Cells – Anatomy, Functions, Clinical Significance
Plasma cells are differentiated B-lymphocyte white blood cells capable of secreting immunoglobulin, or antibody. These cells play a significant role in the adaptive immune response, namely, being the main cells responsible for humoral immunity. Without their presence, an individual is Read More …