Macrolides are groups of antibiotics that are bacteriostatic agents & inhibit bacterial protein synthesis by binding reversibly to 50S ribosomal subunits of sensitive micro-organisms. It is a class of antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), a type of soil-borne bacteria. Macrolides inhibit protein Read More …
Month: May 2018
Diuretic; Types, Mechanism, Uses, Side Effects, Interactions
Diuretic is any substance that promotes diuresis, the increased production of urine. This includes forced diuresis. There are several categories of diuretics. All diuretics increase the excretion of water from bodies, although each class does so in a distinct way. Alternatively, an antidiuretic such as vasopressin(antidiuretic hormone), is an Read More …
Angiotensin II receptor blockers (ARBs); Types, Uses, Effects
Angiotensin II receptor blockers (ARBs), also known as angiotensin II receptor antagonists, AT1 receptor antagonists or sartans, are a group of pharmaceuticals that modulate the renin-angiotensin system. Their main uses are in the treatment of hypertension (high blood pressure), diabetic nephropathy(kidney damage due to diabetes) and congestive heart failure. They block the activation of AT1 receptors, Read More …
Calcium Channel Blockers; Types, Side Effects, Interactions
Calcium channel blockers or calcium channel antagonists or calcium antagonists are several medications that disrupt the movement of calcium (Ca 2+ ) through calcium channels. It is prescription medications that relax blood vessels and increase the supply of blood and oxygen to the Read More …
SSRIs (Selective Serotonin Reuptake Inhibitors)/SNRIs; Types
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders. It is an antidepressant that helps to relieve symptoms of depression such as low mood, irritability, Read More …
Tricyclic Antidepressants; Uses, Side Effects, Interactions
Tricyclic antidepressants with anticholinergic and sedative properties. Amitriptyline appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines. Read More …
Immunosuppressant Drug; Types, Side Effects, Interactions
Immunosuppressant drug is a kind of agent or drugs that suppress the immune system and reduce the risk of rejection of foreign bodies such as transplant organs. Different classes of immunosuppressive agents have different mechanism of action. Now immunosuppressive agents are used as cancer chemotherapy. Read More …
Appetite Loss; Causes, Symptoms, Diagnosis, Treatment
Appetite loss is the desire to eat food, sometimes due to hunger. Appealing foods can stimulate appetite even when hunger is absent, although appetite can be greatly reduced by satiety. Appetite exists in all higher life-forms and serves to regulate adequate energy intake to maintain metabolic needs. It Read More …
Ulcerative Colitis; Causes, Symptoms, Diagnosis, Treatment
Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum. It causes irritation and swelling called inflammation. Eventually, that leads to sores called ulcers in the lining there. It is a chronic inflammation of the large intestine (colon). The colon is the part of the digestive Read More …
Crohn’s Disease; Causes, Symptoms, Diagnosis, Treatment
Crohn’s disease is a chronic long-term type condition of inflammatory bowel disease that may affect any part of the gastrointestinal tract from mouth to anus. It causes inflammation of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition. Crohn’s disease, Read More …
Anakinra; Uses, Dosage, Side Effects, Drug Interactions
Anakinra is a biopharmaceutical drug used to treat rheumatoid arthritis It is a recombinant and slightly modified version of the human interleukin 1 receptor antagonist protein. It is a recombinant, nonglycosylated human interleukin-1 receptor antagonist (IL-1Ra). The difference between anakinra and the native human IL-1Ra is Read More …
Golimumab; Uses, Dosage, Side Effects, Interactions
Golimumab is a human monoclonal antibody which is used as an immunosuppressive drug. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor(VEGF) demonstrates golimumab as Read More …