Month: May 2018

Cefotiam Hydrochloride is the hydrochloride salt form of cefotiam, a second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is Read More …

Ceforanide is a semi-synthetic, broad-spectrum, beta-lactam, a second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin-binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell Read More …

Cefonicid is a second-generation semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and Read More …

Cefamandole is a second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole is active against Haemophilus and gram-negative bacilli susceptible to other cephalosporins. It is also active against many strains resistant to other cephalosporins, such as Enterobacter species and indole-positive Proteus species. Cefamandole is only found in Read More …

Cefoxitin is a semisynthetic, broad-spectrum, second-generation cephalosporin with antibacterial activity. Cefoxitin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in Read More …

Cefotetan is a semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms. Cefotetan is Read More …

Cefuzonam is an injectable, semi-synthetic second-generation cephalosporin with broad-spectrum antibiotic activity.it is a second-generation cephalosporin type of antibiotic medication used to treat bacterial infections. Its antibacterial activity is due to the presence of a beta-lactam core structure, which binds with penicillin-binding Read More …

Penicillins are a group of antibiotics that are bactericidal beta-lactam antibiotics and inhibit bacterial cell wall synthesis. It is a group of antibiotics which include penicillin G (intravenous use), penicillin V (use by mouth), procaine penicillin, and benzathine penicillin (intramuscular use). Penicillin antibiotics were among the first medications to be effective against many bacterial infections caused Read More …

Cephalosporins are a large group of B-lactam antibiotics that are closely related to the penicillins. Cephalosporins penetrate well into most body fluids and the ECF of most tissues, especially when inflammation (which enhances diffusion) is present. Cephalosporins are bactericidal and have the same Read More …