Category: Enzymes and Hormonal Diseases (A – Z)

Empty sella syndrome (ESS) is a condition where the small bony space in the skull that holds the pituitary gland (the sella turcica) looks “empty” on brain scans. In reality, it is not truly empty. The space is filled with Read More …

Central diabetes insipidus (CDI) is a disease where the brain does not make or release enough of a hormone called antidiuretic hormone (ADH), also called vasopressin. ADH is normally made in a part of the brain called the hypothalamus and Read More …

hCG insensitivity is a rare genetic hormone problem where the body cannot “hear” the message from the hormone human chorionic gonadotropin (hCG) and its twin hormone luteinizing hormone (LH). hCG and LH normally bind to a special “antenna” on cells Read More …

LH insensitivity means that the body does not respond properly to luteinizing hormone (LH), even when the blood level of LH is normal or high. LH normally binds to LH receptors on the gonads (testes in males, ovaries in females) Read More …

FSH insensitivity is a rare hormone disorder in which the body makes normal or even very high levels of follicle-stimulating hormone (FSH), but the ovaries in females or the testes in males do not respond properly to it. This happens Read More …

GnRH insensitivity is a rare hormone problem where the body’s cells do not respond properly to gonadotropin-releasing hormone (GnRH). GnRH is made in the brain and tells the pituitary gland to release LH and FSH, which then stimulate the testes Read More …

Secondary adrenal insufficiency is a condition where your adrenal glands do not make enough of the stress hormone cortisol because the pituitary gland in your brain is not sending enough ACTH (adrenocorticotropic hormone) to tell them to work. The adrenal Read More …

ACTH deficiency means the body does not make enough ACTH (adrenocorticotropic hormone), a hormone released by the pituitary gland in the brain. Low ACTH causes the adrenal glands to make too little cortisol, leading to “secondary adrenal insufficiency.” MSD Manuals+1 Read More …

Hypoprolactinemia means that the level of the hormone prolactin in the blood is lower than normal. Prolactin is made by the anterior pituitary gland, a small gland at the base of the brain. Prolactin helps with breast development, milk production Read More …

Isolated growth hormone deficiency (IGHD) is a condition where the pituitary gland does not make enough growth hormone, but the other pituitary hormones are normal. Growth hormone is a chemical messenger that helps children grow in height, build muscle, and Read More …

Growth hormone deficiency (GHD) is a condition where the pituitary gland in the brain does not make enough growth hormone (GH) for the body’s needs. Growth hormone helps children grow taller, build strong bones and muscles, and also supports heart, Read More …

Kallmann syndrome is a rare birth condition where the brain does not make enough of a hormone called GnRH (gonadotropin-releasing hormone). Because of this, the body cannot start or complete puberty in the normal way, and the person has a Read More …