Sparfloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription. Sparfloxacin was withdrawn from the U.S. market due to a high incidence of phototoxicity. Sparfloxacin is a fluoroquinolone antibiotic used in the treatment of bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA Read More …
Category: Drugs A-Z
Ofloxacin; Uses, Dosage, Side effects, Interactions, Pregnancy
Ofloxacin is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. (NCI04) Ofloxacin is a second generation fluoroquinolone that was previously used widely for therapy Read More …
Levofloxacin; Uses, Dosage, Side Effects, Interactions, Pregnancy
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of Read More …
Cigarette Smoking and Its Impact on Bones of Spine with its treatment
Cigarette Smoking is the practice of smoking tobacco and inhaling tobacco smoke consisting of particle and gaseous phases. A more broad definition may include simply taking tobacco smoke into the mouth, and then releasing it, as is done by some with tobacco pipes and cigars. The practice is Read More …
Ciprofloxacin; Uses, Dosage, Side Effects, Interactions, Pregnancy
Ciprofloxacin is a synthetic broad spectrum fluoroquinolone antibiotic. The chemical classification of ciprofloxacin is Quinolones. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. Ciprofloxacin is a broad-spectrum antimicrobial carboxyfluoroquinoline.The bactericidal action Read More …
Cefuroxime; Indications/Uses, Dosage, Side Effects, Interactions
Cefuroxime is a semisynthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin with antibacterial activity. Cefuroxime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and Read More …
Cefixime; Indications/Uses, Dosage, Side Effects, Interactions,
Cefixime is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell Read More …
Azithromycin – Uses, Dosage, Side Effects, Interactions
Azithromycin is a semi-synthetic macrolide antibiotic structurally derived from erythromycin, and a member of a subclass of macrolide antibiotics with bacteriocidal and bacteriostatic activities. It has been used in the treatment of Mycobacterium avium intracellular infections, toxoplasmosis, and cryptosporidiosis. Azithromycin reversibly binds Read More …
Tolperisone Uses, Dosage, Side Effects, Interactions, Pregnancy
Tolperisone is an oral centrally acting muscle relaxant. Tolperisone is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm . Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. It possesses Read More …
Baclofen, Uses, Dosage, Side Effects, Interactions ,Pregnancy
Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors. It acts at spinal and supraspinal sites, reducing excitatory transmission. Baclofen is a Read More …
Gabapentin; Uses, Dosage, Side Effects, Interactions, Pregnan
Gabapentin is a unique anticonvulsant that is used as adjunctive therapy in the management of epilepsy and for neuropathic pain syndromes. Therapy with gabapentin is not associated with serum aminotransferase elevations, but several cases of clinically apparent liver injury from gabapentin have been reported. Gabapentin is Read More …
Pregabalin; Uses, Dosage, Side Effects, Interactions, Pregnanc
Pregabalin is a gamma-aminobutyric acid (GABA) derivative that functions as a calcium channel blocker and is used as an anticonvulsant as well as an anti-anxiety agent. It is also used as an analgesic in the treatment of neuropathic pain and Read More …