Paroxetine is a selective serotonin reuptake inhibitor (SSRI) used in the therapy of depression, anxiety disorders and obsessive-compulsive disorder. Paroxetine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury. Read More …
Category: Drugs A-Z
Multivitamin; Types, Daily Requirement Human Body
Multivitamin is a preparation intended to serve as a dietary supplement – with vitamins, dietary minerals, and other nutritional elements. Such preparations are available in the form of tablets, capsules, pastilles, powders, liquids, or injectable formulations. In healthy people, most scientific evidence indicates that multivitamin supplements Read More …
Fluoxetine; Uses, Dosage, Side Effects, Interactions, Pregnancy
Fluoxetine hydrochloride is the first agent of the class of antidepressants known as selective serotonin-reuptake inhibitors (SSRIs). Despite distinct structural differences between compounds in this class, SSRIs possess similar pharmacological activity. As with other antidepressant agents, several weeks of therapy may be Read More …
Citalopram; Uses, Dosage, Side Effects, Interactions, Pregnancy
Citalopram is a bicyclic naphthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopramselectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions Read More …
Escitalopram; Uses, Dosage, Side Effects, Interactions, Pregnancy
Escitalopram is the active S-stereoisomer of the selective serotonin reuptake inhibitor (SSRI) citalopram with an antidepressant, anti-obsessive-compulsive and antibulimic properties. Escitalopram inhibits the reuptake of the neurotransmitter serotonin (5-HT) at the serotonin reuptake pump of the neuronal membrane of the presynaptic cell, thereby increasing levels of 5-HT within the synaptic cleft and enhancing Read More …
Mebendazole; Uses, Dosage, Side Effects, Interactions, Pregnancy
Mebendazole is a synthetic benzimidazole derivate an anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen stores and leads to reduced formation of ATP required for Read More …
Flubendazole; Uses, Dosage, Side Effects, Interactions, Pregnancy
Flubendazole is an anthelmintic. Its brand name is Flutelmium which is a paste manufactured by Janssen Pharmaceutica N.V. used by veterinarians for protection against internal parasites and treat worm infection in humans. Mechanism of Action of Flubendazole The molecular mode of action of all benzimidazoles, including flubendazole, consists in binding to tubulin, a structural protein Read More …
Albendazole; Uses, Dosage, Side Effects, Interactions, Pregnancy
Albendazole is a broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm’s death. Albendazole is used in the treatment Read More …
Econazole; Uses, Dosage, Side Effects, Interactions, Pragnancy
Econazole is only found in individuals that have used or taken this drug. It is a broad spectrum antimycotic with some action against Gram-positive bacteria. It is used topically in dermatomycoses also orally and parenterally. [PubChem]Econazole interacts with 14-alpha-demethylase, a cytochrome P-450 Read More …
Isavuconazole; Uses, Dosage, Side Effects, Interactions, Pragnancy
Isavuconazole is a water-soluble triazole prodrug with broad-spectrum antifungal activity. Isavuconazole is absorbed easily, given either orally or intravenously, and is hydrolyzed to its active moiety BAL4815 by plasma esterases. BAL4815 inhibits fungal cytochrome P450 lanosterol 14-alpha-demethylase (CYP51) that catalyzes the conversion of lanosterol to ergosterol, an important component of the fungal cell membrane. Enzyme Read More …
Posaconazole; Uses, Dosage, Side Effects, Interactions, Pragnancy
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha-demethylase, a cytochrome P450-dependent enzyme. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Inhibition of ergosterol synthesis changes the fungal cell membrane composition and integrity, alters Read More …
Itraconazole; Uses, Dosage, Side Effects, Interactions, Pragnancy
Itraconazole is a synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fungal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of Read More …