Penicillins are a group of antibiotics that are bactericidal beta-lactam antibiotics and inhibit bacterial cell wall synthesis. It is a group of antibiotics which include penicillin G (intravenous use), penicillin V (use by mouth), procaine penicillin, and benzathine penicillin (intramuscular use). Penicillin antibiotics were among the first medications to be effective against many bacterial infections caused Read More …
Category: Drugs A-Z
Cephalosporins; Types, Uses, Contraindications, Side Effects, Interactions,
Cephalosporins are a large group of B-lactam antibiotics that are closely related to the penicillins. Cephalosporins penetrate well into most body fluids and the ECF of most tissues, especially when inflammation (which enhances diffusion) is present. Cephalosporins are bactericidal and have the same Read More …
Macrolides; Types, Indications, Side Effects, Interactions
Macrolides are groups of antibiotics that are bacteriostatic agents & inhibit bacterial protein synthesis by binding reversibly to 50S ribosomal subunits of sensitive micro-organisms. It is a class of antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), a type of soil-borne bacteria. Macrolides inhibit protein Read More …
Diuretic; Types, Mechanism, Uses, Side Effects, Interactions
Diuretic is any substance that promotes diuresis, the increased production of urine. This includes forced diuresis. There are several categories of diuretics. All diuretics increase the excretion of water from bodies, although each class does so in a distinct way. Alternatively, an antidiuretic such as vasopressin(antidiuretic hormone), is an Read More …
Angiotensin II receptor blockers (ARBs); Types, Uses, Effects
Angiotensin II receptor blockers (ARBs), also known as angiotensin II receptor antagonists, AT1 receptor antagonists or sartans, are a group of pharmaceuticals that modulate the renin-angiotensin system. Their main uses are in the treatment of hypertension (high blood pressure), diabetic nephropathy(kidney damage due to diabetes) and congestive heart failure. They block the activation of AT1 receptors, Read More …
Calcium Channel Blockers; Types, Side Effects, Interactions
Calcium channel blockers or calcium channel antagonists or calcium antagonists are several medications that disrupt the movement of calcium (Ca 2+ ) through calcium channels. It is prescription medications that relax blood vessels and increase the supply of blood and oxygen to the Read More …
SSRIs (Selective Serotonin Reuptake Inhibitors)/SNRIs; Types
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders. It is an antidepressant that helps to relieve symptoms of depression such as low mood, irritability, Read More …
Tricyclic Antidepressants; Uses, Side Effects, Interactions
Tricyclic antidepressants with anticholinergic and sedative properties. Amitriptyline appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines. Read More …
Immunosuppressant Drug; Types, Side Effects, Interactions
Immunosuppressant drug is a kind of agent or drugs that suppress the immune system and reduce the risk of rejection of foreign bodies such as transplant organs. Different classes of immunosuppressive agents have different mechanism of action. Now immunosuppressive agents are used as cancer chemotherapy. Read More …
Anakinra; Uses, Dosage, Side Effects, Drug Interactions
Anakinra is a biopharmaceutical drug used to treat rheumatoid arthritis It is a recombinant and slightly modified version of the human interleukin 1 receptor antagonist protein. It is a recombinant, nonglycosylated human interleukin-1 receptor antagonist (IL-1Ra). The difference between anakinra and the native human IL-1Ra is Read More …
Golimumab; Uses, Dosage, Side Effects, Interactions
Golimumab is a human monoclonal antibody which is used as an immunosuppressive drug. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor(VEGF) demonstrates golimumab as Read More …
Infliximab; Uses, Dosage, Side Effects, Drug Interactions
Infliximab is a chimeric monoclonal antibody biologic drug that works against tumor necrosis factor alpha (TNF-α) and is used to treat autoimmune diseases. It is an antibody administered intravenously that is used for treating several chronic inflammatory diseases. Infliximab works by blocking the effects of tumor necrosis factor alpha (TNF Read More …