Modafinil is a synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04) Modafinil and its R-enantiomer armodafinil are Read More …
Category: Drugs A-Z
Best Drugs for Constipation; Types, Uses
Best Drugs for Constipation refers to bowel movements that are infrequent or hard to pass.[rx] The stool is often hard and dry.[rx] Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. Complications from constipation may include hemorrhoids, anal Read More …
Suvorexant; Uses, Dosage, Side Effects, Interactions
Suvorexant is an Orexin Receptor Antagonist. The mechanism of action of suvorexant is as an Orexin Receptor Antagonist, and P-Glycoprotein Inhibitor, and Cytochrome P450 3A Inhibitor. Suvorexant is an orexin receptor antagonist used for the treatment of insomnia and sleep disorders. Suvorexant therapy is associated with Read More …
Desvenlafaxine; Uses, Dosage, Side Effects, Interactions
Desvenlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. O-Desmethylvenlafaxine is a metabolite of Venlafaxine. Desvenlafaxine (brand name: Read More …
Viagra Treatment for all with the ‘little blue pill…
Viagra treatment for all with the ‘little blue pill…Study results suggest that PDE-5 inhibitors could have a role in treating cancer, heart failure, neurodegenerative diseases, circulatory disorders, and even infectious diseases, but the road to approval for new indications may Read More …
Venlafaxine; Uses, Dosage, Side Effects, Interactions
Venlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04) Venlafaxine is a serotonin and norepinephrine reuptake inhibitor widely used as an antidepressant. Venlafaxine therapy can be associated with transient asymptomatic Read More …
Acemetacin; Uses, Dosage, Site Effects, Interactions
Acemetacin is a carboxymethyl ester of indomethacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin. It Read More …
Bryonia; Uses, Dosage, Site Effects, Interactions
Bryonia a well-known medicinal plant used mainly in homeopathy as an anti- inflammatory, has never been considered an adaptogen. However, much evidence has been accumulated during the last decade indicating that Bryonia roots have adaptogenic properties. This review summarizes the Read More …
Podophyllin; Uses, Dosage, Site Effects, Interactions
Podophyllin is a resin extracted from the root of the plant Podophyllum sp. Berberidaceae (Mandrake), which contains numerous compounds, among which podophyllotoxin. Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase. Caustic extract from the roots of Podophyllum peltatum and P. emodi. Podophyllum resin Read More …
Magnesium Carbonate; Uses, Dosage, Effects, Interactions
Magnesium carbonate also is known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach. MAGNESITE is a white, yellowish, grayish-white or brown crystalline solid or crystalline powder. Read More …
Aconitine; Uses, Dosage, Site Effects, Interactions, Pregnancy
Aconitine is a C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM plants. It activates VOLTAGE-GATED SODIUM CHANNELS. It has been used to induce ARRHYTHMIAS in experimental animals and it has anti-inflammatory and antineuralgic properties. Aconitine is a diterpenoid that is Read More …
Pefloxacin; Uses, Dosage, Side Effects, Interactions, Pregnanc
Pefloxacin is a fluoroquinolone antibiotic with broad-spectrum antimicrobial activity. Pefloxacin inhibits the activity of microbial DNA gyrase and topoisomerase IV. This disrupts DNA replication and prevents cell division. Pefloxacin is only found in individuals that have used or taken this drug. It is a synthetic broad-spectrum fluoroquinolone antibacterial Read More …