Category: Cancer, Neoplasms and Palliative Care A – Z

Eosinophilic Pneumonia includes a group of disorders characterized by an accumulation of eosinophilic infiltrates in the pulmonary parenchyma with/without peripheral blood eosinophilia. These include a broad range of lung conditions that occur due to infectious or non-infectious causes. Eosinophilic pneumonia is Read More …

Leukocyte Adhesion Deficiency (LAD) is a defect of cellular adhesion molecules resulting in clinical syndromes. It is a combined (B cell) and cellular (T cell) immunodeficiency disorder. Leukocyte adhesion deficiency (LAD), is a rare autosomal recessive disorder characterized by immunodeficiency resulting in recurrent infections.[rx] LAD is currently divided Read More …

Lymphocytosis defined by an increase in absolute lymphocyte count (ALC) to more than 4000 lymphocytes/microL in adult patients, is a common hematologic abnormality. ALC calculates as the total white blood cell count (WBC) multiplied by the percentage of lymphocytes in Read More …

Immunity/The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism’s own healthy tissue. In many Read More …

Felty Syndrome (FS) is an uncommon extra-articular manifestation of seropositive rheumatoid arthritis (RA) characterized by RA, neutropenia, and splenomegaly. Felty syndrome was first described in 1924 at Johns Hopkins hospital by the American physician, Augustus Felty. He described five unusual Read More …

Periodic Neutropenia/Cyclic Neutropenia is a very rare hematological condition and is characterized by regular fluctuations in blood neutrophil counts, leading to periodic neutropenia with a 21-day turnover frequency.[rx][rx] It is now considered an autosomal dominant disease caused by ELANE gene mutations.[rx] The Read More …

Cyclic Hematopoiesis/Cyclic Neutropenia is a very rare hematological condition and is characterized by regular fluctuations in blood neutrophil counts, leading to periodic neutropenia with a 21-day turnover frequency.[rx][rx] It is now considered an autosomal dominant disease caused by ELANE gene mutations.[rx] The Read More …

Cyclic Neutropenia is a very rare hematological condition and is characterized by regular fluctuations in blood neutrophil counts, leading to periodic neutropenia with a 21-day turnover frequency.[rx][rx] It is now considered an autosomal dominant disease caused by ELANE gene mutations.[rx] The symptoms Read More …

Neutropenic Fever is when there is a single oral temperature of greater than or equal to 101 F, or a temperature greater than or equal to 100.4 F for at least an hour, with an absolute neutrophilic count (ANC) of Read More …

Febrile Neutropenia is the development of fever, often with other signs of infection, in a patient with neutropenia, an abnormally low number of neutrophil granulocytes (a type of white blood cell) in the blood. The term neutropenic sepsis is also applied, although it tends to be reserved for patients Read More …

Autoimmune Neutropenia your body makes antibodies that fight your neutrophils. These antibodies kill the neutrophils, and this causes neutropenia. Autoimmune neutropenia develops later in life. Neutropenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood.[4] Neutrophils make up Read More …

Congenital Neutropenia is present at birth. Severe congenital neutropenia is also called Kostmann syndrome. It causes very low neutrophil levels. In some cases, neutrophils are absent. This puts infants and young children at risk for serious infections. Neutropenia is an abnormally Read More …