Category: Cancer, Neoplasms and Palliative Care A – Z

Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML; see this term) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with Read More …

Acute Megacaryoblastic Leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) characterized by abnormal megakaryoblasts that express platelet-specific surface glycoprotein. Bone marrow biopsy frequently demonstrates extensive myelofibrosis, often making aspiration in these patients difficult. AMKL is extremely rare in Read More …

Acute Erythroid Leukemia/Acute Erythroleukemia is a rare form of acute myeloid leukemia recognized by its distinct phenotypic attribute of erythroblast proliferation. After a century of its descriptive history, many diagnostic, prognostic, and therapeutic implications relating to this unique leukemia subset Read More …

Acute Erythroleukemia is a rare form of acute myeloid leukemia recognized by its distinct phenotypic attribute of erythroblast proliferation. After a century of its descriptive history, many diagnostic, prognostic, and therapeutic implications relating to this unique leukemia subset remain uncertain. Read More …

Acute Promyelocytic Leukemia is a distinguished subset of acute myeloid leukemia which is characterized by fusion gene transcript PML-RAR-alpha and high cure rates with treatment. This entity was first described in 1957 in patients with severe bleeding tendencies with fibrinolysis, Read More …

Acute Megakaryoblastic Leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) characterized by abnormal megakaryoblasts that express platelet-specific surface glycoprotein. Bone marrow biopsy frequently demonstrates extensive myelofibrosis, often making aspiration in these patients difficult. AMKL is extremely rare in Read More …

Acute Non-Lymphocytic Leukemia/An aggressive (fast-growing) disease in which too many myeloblasts (immature white blood cells that are not lymphoblasts) are found in the bone marrow and blood. Also called acute myeloblastic leukemia, acute myelogenous leukemia, acute myeloid leukemia, AML, and Read More …

Acute Myelogenous Leukemia /Acute myelocytic leukemia (AML) is a disorder of uncontrolled proliferation of undifferentiated myeloid precursor cells. This leads to the accumulation of immature myeloid cells, myeloblasts, in the bone marrow, and usually their presence in the peripheral blood. Read More …

Acute Myelocytic Leukemia/Acute myelocytic leukemia (AML) is a disorder of uncontrolled proliferation of undifferentiated myeloid precursor cells. This leads to the accumulation of immature myeloid cells, myeloblasts, in the bone marrow, and usually their presence in the peripheral blood. Acute Read More …

Acute Myeloid Leukemia (AML) is a group of hematological diseases, phenotypic and genetically heterogeneous, characterized by abnormal accumulation of blast cells in the bone marrows and peripheral blood. Acute myeloid leukemia (AML) is the most common leukemia among the adult Read More …

Chronic Lymphocytic Leukemia is a chronic lymphoproliferative disorder characterized by monoclonal B cell proliferation. It is the most common adult leukemia in Western populations. Chronic lymphocytic leukemia (CLL) is a malignancy of CD5+ B cells that is characterized by the Read More …

Lymphoblastic Leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain.[rx] As an acute leukemia, ALL progresses rapidly and is typically fatal Read More …