B-cell Prolymphocytic Leukemia (B-PLL) is a rare, aggressive leukemia distinct from chronic lymphocytic leukemia. B-PLL is resistant to most chemotherapy and newer targeted therapies such as alemtuzumab and thalidomide. Phenylethyl isothiocyanate (PEITC) is a natural compound from horseradish with evidence Read More …
Month: October 2020
Lymphoproliferative Disorders – Symptoms, Treatment
Lymphoproliferative Disorders (LPD) comprise a heterogeneous group of diseases characterized by uncontrolled production of lymphocytes that cause monoclonal lymphocytosis, lymphadenopathy and bone marrow infiltration. These diseases often occur in immunocompromised individuals. There are two subsets of lymphocytes: T and B Read More …
Monoclonal B Lymphocytosis – Diagnosis, Treatment
Monoclonal B Lymphocytosis (MBL) is defined as the presence of a clonal B-cell population in the peripheral blood with fewer than 5 × 109/L B-cells and no other signs of a lymphoproliferative disorder. The majority of cases of MBL have Read More …
Lymphoma – Causes, Symptoms, Diagnosis, Treatment
Lymphoma are a heterogeneous group of malignancies that arise from the clonal proliferation of B- cell, T- cell and natural killer (NK) cell subsets of lymphocytes at different stages of maturation.[rx][rx] Lymphoma comprises heterogeneous malignancies that arise from the clonal proliferation of lymphocytes. It Read More …
Non-Hodgkin Lymphoma – Causes, Symptoms, Treatment
Non-Hodgkin lymphoma (NHL) is a neoplasm of the lymphoid tissues, which originates from B cell precursors, mature B cells, T cell precursors, and mature T cells. Non-Hodgkin lymphoma comprises of various subtypes, each with different epidemiologies, etiologies, immunophenotypic, genetic, clinical features, and response Read More …
Chronic Lymphocytic Leukemia – Symptoms, Treatment
Chronic Lymphocytic Leukemia is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). Chronic lymphocytic leukemia is characterized by clonal proliferation and progressive accumulation of B-cell lymphocytes that typically express Read More …
Childhood Leukemia – Causes, Symptoms, Treatment
Childhood Leukemia is a leukemia that occurs in a child and is a type of childhood cancer. Childhood leukemia is the most common childhood cancer, accounting for 29% of cancers in children aged 0–14 in 2018.[1] There are multiple forms of leukemia that Read More …
Blood Cancer Drugs – FDA Approved Latest Drug Types
Blood Cancer Drugs/This page lists cancer drugs approved by the Food and Drug Administration (FDA) for leukemia. The list includes generic and brand names. This page also lists common drug combinations used in leukemia. The individual drugs in the combinations Read More …
Chronic Myelogenous Leukemia – Symptoms, Treatment
Chronic Myelogenous Leukemia BCR–ABL1+ (CML) is a myeloproliferative neoplasm that originates in a pluripotent bone marrow stem cell and is consistently associated with the BCR–ABL1 fusion gene. This genetic abnormality results from the translocation of ABL1 on chromosome 9 to the region of Read More …
Drugs For Blood Cancer – FDA Approved Drugs A to Z
Drugs For Blood Cancer/This page lists cancer drugs approved by the Food and Drug Administration (FDA) for leukemia. The list includes generic and brand names. This page also lists common drug combinations used in leukemia. The individual drugs in the Read More …
Chronic Myeloid Leukemia – Causes, Symptoms, Treatment
Chronic Myeloid Leukemia (CML) is a cancer of blood cells, characterized by replacement of the bone marrow with malignant, leukemic cells. Many of these leukemic cells can be found circulating in the blood and can cause enlargement of the spleen, Read More …
Acute Myelosclerosis – Causes, Symptoms, Treatment
Acute Myelosclerosis/Acute Panmyelosis with Myelofibrosis (APMF) is a rare form of acute myeloid leukemia and is characterized by acute panmyeloid proliferation with increased blasts and accompanying fibrosis of the bone marrow that does not meet the criteria for AML with Read More …