Month: August 2020

Lofgren Syndrome is a clinically distinct phenotype of sarcoidosis, first described in 1946 by Swedish pulmonologist Sven Lofgren. Sarcoidosis is a multisystem granulomatous disorder of unknown etiology that commonly involves the lungs with the second most commonly affected organ being Read More …

Erythema Nodosum (EN) is a common acute nodular septal panniculitis, characterized by the sudden onset of erythematous, firm, solid, deep nodules or plaques that are painful on palpation and mainly localized on extensor surfaces of the legs. These nodules are Read More …

Erythema Multiforme (EM) is a cutaneous and mucosal hypersensitivity reaction with characteristic lesions in target triggered by certain antigenic stimuli. It represents an acute condition, sometimes recurrent, of the skin and mucosal membranes manifested by papular, bullous, and necrotic lesions. Read More …

Behcet Disease was first described in 1937 by Hulusi Behçet from Istanbul, who described three patients with oral and genital ulcerations, uveitis, and erythema nodosum. Other clinical features were identified later and were added to the disease spectrum.[1] Behcet disease Read More …

Lichen planus (LP) is an inflammatory disorder of the skin and mucous membranes with no known cause. It appears as pruritic, violaceous papules and plaques most commonly found on the wrists, lower back, and ankles. A lattice-like network of white Read More …

Erosive lichen planus (ELP) is a variant of lichen planus which involves chronic and painful ulceration of the skin and mucosal surfaces. ELP is thought to be the result of autoimmune damage of the basal cell layer, which is mediated Read More …

Poroma (poroid tumor) is a benign adnexal tumor that usually originates from the terminal duct of the sweat gland.[1] Initially, in 1956 Pinkus et al. described poroma and its poroid (terminal ductal) differentiation and had been thought to be from the Read More …

Calcinosis cutis is a condition in which calcium salts are deposited in the skin and subcutaneous tissue. It is classified into five main types: dystrophic, metastatic, idiopathic, iatrogenic, and calciphylaxis. Dystrophic calcification is the most common cause of calcinosis cutis Read More …

Porokeratosis is an uncommon dermatologic disorder. It is a disorder of keratinization that presents with keratotic papules or annular plaques with an elevated border.[1] It has a distinct histologic hallmark of cornoid lamella, which is a column of tightly fitted parakeratotic cells in Read More …

Arsenical keratosis is a precancerous dermatosis seen in patients with chronic arsenic toxicity (CAT).[1] It is characterized by corn-like, yellowish, hyperkeratotic papules and plaques, primarily affecting the palms and soles. Often it starts as small areas of hyperkeratosis, which increase in Read More …

Palmoplantar psoriasis is a variant of psoriasis that characteristically affects the skin of the palms and soles. It features hyperkeratotic, pustular, or mixed morphologies. Palmoplantar pustulosis, or pustular palmoplantar psoriasis, is a possibly related dermatosis characterized by small, sterile pustules Read More …

Warty dyskeratoma (WD) is a benign endophytic cutaneous lesion, characterized by proliferation of squamous epithelium, acantholysis, and dyskeratosis (Weedon et al. 2005). Based on its regular association with pilosebaceous units, it has been suggested that WD is a true benign follicular Read More …