Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in Read More …
Month: January 2018
Tiemonium Methylsulfate, Indications/Uses, Side Effects, Interactions
Tiemonium Methylsulfate is a synthetic antispasmodic agent. Tiemonium strengthens calcium bonding with phospholipids and proteins thus stabilizing the cell membrane of the GI tract.Tiemonium Methylsulphate is a quarternary ammonium antimuscarinic agent with spasmolytic (antispasmodic) and parasympatholytic (anticholinergic) effects and is Read More …
Dolasetron, Indications, Dosage, Side Effect, Interactions, Pregnancy
Dolasetron is an indole derivative and a potent serotonin 5-HT3 receptor antagonist with the anti-emetic property. Dolasetron blocks the activity of serotonin released from the enterochromaffin cells of the small intestine by selectively inhibiting and inactivating 5-HT3 receptors located on the nerve terminals of the vagus nerve in Read More …
Granisetron; Indications, Dosage, Side Effect, Interactions, Pregnancy
Granisetron is an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Granisetron is a Serotonin-3 Receptor Antagonist. The mechanism of action of granisetron is as a Serotonin 3 Receptor Antagonist. Read More …
Palonosetron, Indications, Dosage, Side Effect, Interactions, Pregnancy
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the Read More …
Ondansetron; Uses, Dosage, Side Effects, Interactions, Pregnancy
Ondansetron is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Ondansetron is a carbazole derivative with antiemetic activity. As a Read More …
Domperidone; Indications, Dosage, Side Effects, Interactions ,Pregnancy
Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms. Domperidone is a peripheral-specific antagonist of the dopamine receptor D2 (D2R), with antiemetic, gastrokinetic and Read More …
Loperamide, Indications, Dosage, Side Effects, Interactions, Pregnancy
Loperamide is a synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastrointestinal motility by effects on the circular and longitudinal muscles of the intestine. Part of its anti-diarrheal effect may be due to a reduction of gastrointestinal secretion produced Read More …
Nitazoxanide, Indications, Dosage, Side Effects, Interactions, Pregnancy
Nitazoxanide is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction, which is essential to anaerobic energy metabolism. PFOR enzyme reduces nitazoxanide, thereby impairing the energy metabolism. However, interference with the PFOR enzyme-dependent electron Read More …
Metronidazole, Indications, Dosage, Side Effects, Interactions
Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes Read More …
Medication/Drugs; Disease Conditions, Treatment,
Medication/Drugs is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body. In pharmacology, a drug is a chemical substance of known structure, other than Read More …
Antidiabetes Drugs; Indications, Side Effects, Drug Interactions
Antidiabetes drugs is used in diabetes treat diabetes mellitus by lowering glucose levels in the blood. With the exceptions of insulin, exenatide, liraglutide and pramlintide, all are administered orally and are thus also called oral hypoglycemic agentsor oral antihyperglycemic agents. There are different classes of anti-diabetic drugs, and their selection depends Read More …