Hormone Replacement Therapy – Indications, Contraindications

Hormone Replacement Therapy (HRT) is a special kind of supplementing therapy for women with hormones that lost during menopausal time or transition periods. To relieve the symptoms associated with hormonal deficiency menopause, conventional HRT includes an estrogen and progesterone component to mimic hormones created by the human ovary. Estrogen therapies are numerous, and include those … [Read more…]

What Is Melanoma? – Causes, Symptoms, Diagnosis, Treatment

Retinoblastoma

Melanoma of the uveal tract (iris, ciliary body, and choroid), though rare, is the most common primary intraocular malignancy in adults. The mean age-adjusted incidence of uveal melanoma in the United States is approximately 4.3 new cases per million people, with no clear variation by latitude. Males have a higher incidence at 4.9 cases per … [Read more…]

Hemifacial Spasm – Causes, Symptoms, Treatment

Hemifacial spasm (HFS) is a disorder characterized by paroxysmal, involuntary twitching of facial muscles of one side of face innervated by ipsilateral facial nerve (seventh cranial nerve). It is considered a subtype of peripheral (neuromuscular) movement disorder. As the name suggests, the disorder is almost always unilateral except in some rare cases of severe hemifacial … [Read more…]

Paraneoplastic Cerebellar Degeneration – Symptoms, Treatment

Paraneoplastic Cerebellar Degeneration (PCD) is one of the more commonly seen paraneoplastic neurological syndromes. It is caused by immune-mediated injury to cerebellar Purkinje cells. It is associated with multiple malignancies but, most commonly, breast and pelvic malignancies.[rx] PCD has also been reported in patients with Hodgkin lymphoma, gastric cancer, prostate cancer, and small cell lung cancer.[rx][rx] PCD can progress rapidly … [Read more…]

Paraneoplastic Neurological Syndromes – Symptoms, Treatment

Paraneoplastic Neurological Syndromes (PNS) are rare disorders associated with cancer, not caused by direct invasion, metastasis or consequences of treatment. They are usually autoimmune in nature. Often, PNS precedes the manifestations of cancer. Onconeural antibodies are important in the diagnosis and management of these disorders. These antibodies are specific for malignancy rather than for a … [Read more…]

Paraneoplastic Syndromes – Causes, Symptoms, Treatment

Paraneoplastic Syndromes are a group of rare disorders that are triggered by an abnormal immune system response to a cancerous tumor known as a “neoplasm.” Paraneoplastic syndromes are thought to happen when cancer-fighting antibodies or white blood cells (known as T cells) mistakenly attack normal cells in the nervous system. Paraneoplastic syndromes are rare disorders … [Read more…]

Granuloma Pyogenic – Causes, Symptoms, Treatment

Granuloma Pyogenic/Pyogenic Granuloma sometimes known as granuloma pyogenic, refers to a common, acquired, benign, vascular tumor that arises in tissues such as the skin and mucous membranes.[rx] The scientifically accurate term for this entity is the lobular capillary hemangioma.[rx] In the past, pyogenic granulomas were thought to be an exaggerated granulomatous reaction to an infectious … [Read more…]

Pyogenic Granuloma – Causes, Symptoms, Treatment

Pyogenic Granuloma sometimes known as granuloma pyogenic, refers to a common, acquired, benign, vascular tumor that arises in tissues such as the skin and mucous membranes.[rx] The scientifically accurate term for this entity is the lobular capillary hemangioma.[rx] In the past, pyogenic granulomas were thought to be an exaggerated granulomatous reaction to an infectious or … [Read more…]

PHACE Syndrome – Causes, Symptoms, Diagnosis, Treatment

PHACE Syndrome is a rare disorder that affects multiple systems of the body. This disorder is characterized by an association of several different abnormalities that occur together with greater frequency than would otherwise be expected. The term PHACE is an acronym; each letter stands for a word. Infantile hemangioma is the most prevalent benign tumor … [Read more…]