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Hyperthyroid myopathy (also called thyrotoxic myopathy) is a muscle disease that happens when the body has too much thyroid hormone for a long time. The extra hormone speeds up metabolism and makes muscle cells break down faster than they can repair. This mainly affects the big muscles close to the shoulders and hips, and causes…

Amiodarone induced thyrotoxicosis (AIT) is a type of hyperthyroidism that happens because of the heart medicine amiodarone. Amiodarone is an anti-arrhythmic drug that contains a very large amount of iodine, and this extra iodine can disturb the thyroid gland and make it release too much thyroid hormone.Wikipedia+1 Amiodarone-induced thyrotoxicosis (AIT) happens when the heart medicine…

Thyroid storm is a rare, life-threatening emergency that happens when the thyroid gland suddenly releases a very large amount of thyroid hormone into the blood. This causes the body’s systems to “run out of control,” with extremely high fever, very fast heart rate, low blood pressure, confusion, and organ failure if it is not treated…

Thyrotoxicosis factitia is a type of thyrotoxicosis (too much thyroid hormone in the blood) that happens because a person takes thyroid hormone from outside the body, usually in tablet or capsule form, even though their own thyroid gland is not overactive. It may be accidental, due to dosing mistakes, or deliberate, for weight loss or…

Hashitoxicosis is a short-lasting phase of thyrotoxicosis (too much thyroid hormone in the blood) that happens in people with Hashimoto thyroiditis, an autoimmune disease of the thyroid. In this condition, the immune system attacks the thyroid gland and damages the tiny hormone-making sacs (follicles). When these cells break open, they “spill” stored thyroid hormones (T4…

Familial dysalbuminemic hyperthyroxinemia (FDH) is a rare inherited condition in which a change (mutation) in the albumin gene makes blood albumin bind thyroid hormone, especially thyroxine (T4), much more tightly than normal. Because of this, blood tests show very high total T4 levels, but the free (active) thyroid hormone and thyroid-stimulating hormone (TSH) stay in…

Thyroid hormone resistance is a rare condition where body tissues do not respond properly to thyroid hormones (T4 and T3), even though the blood levels of these hormones are high. Because the cells “ignore” part of the hormone signal, the pituitary gland does not switch off thyroid-stimulating hormone (TSH), so TSH stays normal or high…

Hyperthyroxinemia means “too much thyroxine (T4) hormone in the blood.” Thyroxine (T4) is the main hormone made by the thyroid gland in the neck. In this condition, the blood test for T4 is higher than the normal reference range. Sometimes the person really has an overactive thyroid (hyperthyroidism). Sometimes the thyroid itself is normal and…

Lambert–Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease that affects the place where the nerve meets the muscle, called the neuromuscular junction. In LEMS, the immune system makes antibodies that attack voltage-gated calcium channels on the nerve ending. Because of this attack, the nerve cannot release enough of the chemical messenger acetylcholine, so the…

Lambert–Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease that affects the place where nerves talk to muscles, called the neuromuscular junction. In LEMS, the immune system makes antibodies that attack special “gates” (P/Q-type voltage-gated calcium channels) on the nerve ending. When these gates are damaged, much less of the chemical messenger acetylcholine is released,…

Hoffmann syndrome is a rare muscle disease that happens in adults with long-standing, untreated or poorly treated hypothyroidism (low thyroid hormone). In this condition the muscles, especially in the calves, look big and strong from the outside (pseudohypertrophy), but they are actually weak, stiff, and easily tired.PubMed+1 It is a special form of hypothyroid myopathy…

KDSS syndrome is usually short for Kawasaki Disease Shock Syndrome (KDSS). It is a rare but very serious form of Kawasaki disease, which is an illness that causes strong inflammation of small and medium blood vessels in the body, especially in the heart. In KDSS, a child has Kawasaki disease and also develops shock, which…