Nux Vomica; Uses, Dosage, Site Effects, Interactions

Nux Vomica; Uses, Dosage, Site Effects, Interactions

Nux vomica (family Loganiaceae) is commonly known as kuchla. It is a major source of the highly poisonous, intensely bitter alkaloids strychnine and brucine derived from the seeds inside the tree’s round, green to orange fruit.[1] The seeds contain approximately 1.5% strychnine, and the dried blossoms contain 1.0%.[2] However, the tree’s bark also contains brucine and other poisonous compounds. Kuchla contain 2.6%–3% total alkaloids, out of which 1.25%–1.5% is strychnine, 1.7% is brucine, and the rest are vomicine and igasurine.[] Some other minor alkaloids are α-colubrine, β-colubrine, 3-methoxyamine, protostrychnine, novacine, n-oxystrychnine, pseudostrychnine, isostrychnine, chlorogenic acid, and a glycoside, loganin.[] Crude drug kuchla is used in the treatment of anemia, lumbago, asthma, bronchitis, constipation, diabetes, malarial fever, skin disease, paralysis, muscle weakness, and appetite loss.[] Suppressive effect of S. nux-vomica was observed on the induction of ovalbumin-specific IgE antibody response in mice.[] Strychnine was identified and analyzed in detoxified kuchla seeds using liquid chromatography-electrospray mass spectrometry.[] Strychnine and brucine were separated and quantified in S. nux-vomica by nonaqueous capillary electrophoresis.[] Matrix-assisted laser desorption/ionization (MALDI) and time of flight mass spectrometry (TOFMS) analysis of crude and processed S. nux-vomica seeds allowed rapid screening of alkaloid components.[]

STRYCHNINE AND SALTS is a colorless to white crystals. Used as a rodenticide. Burns, though difficult to ignite. Toxic by ingestion. Produces toxic oxides of nitrogen during combustion.

Uses / Indications of Nux Vomica

  • Erectile dysfunction (ED, impotence)
  • Diseases of the stomach and intestines
  • Heart and blood system disorders
  • Tired blood (anemia)
  • Diseases of the eye
  • Nerve disorders
  • Depression
  • A migraine
  • Lung disease
  • Stimulating the appetite
  • Digestive problems such as constipation, bloating, heartburn, and nausea
  • Male infertility and impotence
  • Colds and flus, particularly in the early stages of the virus
  • Allergies
  • Back pain
  • Irritability, impatience, and high sensitivity to stimuli, caused by stress or mental strain
  • Headaches and migraines symptoms such as a sore scalp, frontal pain, light sensitivity, or stomach problems
  • Hangovers
  • Menstrual problems
  • Insomnia
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The Dosage of Nux Vomica

  • Adult and children 2 years of age and older – Dissolve 5 pellets under the tongue 3 times a day until relieved or as directed by a doctor.

or

  • Acute – Take 4 drops per dose orally every 15 minutes for up to 6 doses, then 3 times a day as required.
  • Chronic – Take 4 drops per dose orally 3 times a day as required.

References

Acemetacin

 

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