Cefuzonam; Uses, Contraindications, Dosage, Side effects, Interaction

Cefuzonam; Uses, Contraindications, Dosage, Side effects, Interaction

Cefuzonam is an injectable, semi-synthetic second-generation cephalosporin with broad-spectrum antibiotic activity.it is a second-generation cephalosporin type of antibiotic medication used to treat bacterial infections. Its antibacterial activity is due to the presence of a beta-lactam core structure, which binds with penicillin-binding proteins within bacterial cells, thereby inhibiting cell wall synthesis.

Mechanism of Action of Cefuzonam

Cephalosporins exert bactericidal activity by interfering with bacterial cell wall synthesis and inhibiting cross-linking of the peptidoglycan. The cephalosporins are also thought to play a role in the activation of bacterical cell autolysins which may contribute to bacterial cell lysis.

Indications of Cefuzonam

Contra Indications of Cefuzonam

  • Clostridium difficile infection
  • Decrease in the Blood-Clotting Protein Prothrombin
  • severe renal impairment
  • Liver problems
  • Interstitial Nephritis
  • Subacute cutaneous lupus erythematosus
  • Systemic Lupus Erythematosus
  • Allergies cephalosporins & betalactams

Side Effects of Cefuzonam

The most common

More common

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