Cefclidin; Mechanism, Uses, Contraindications, Dosage, Side effects,

Cefclidin is a fourth-generation, parenteral cephalosporin with strong activity against glucose non-fermentative bacillus bacteria, but is ineffective against gram-positive cocci.

Pharmacology of Cefclidin

Side Effects of Cefclidin

The most common

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• leukopenia/leukemia
• hemolytic anemia
• serum sickness
• agranulocytosis
• pain, swelling, irritation where injected
• stomach upset
• sweating
• skin color change, mild diarrhea
• mild nausea
• loss of appetite
• vaginal discharge and itching
• swelling of feet or legs
• chest pain
• constipation
• cough
• diarrhea or loose stools
• difficulty with breathing
• dizziness
• heartburn

More common

• Abdominal or stomach pain, discomfort, or tenderness
• chills or fever
• difficulty with moving
• headache, severe and throbbing
• joint or back pain
• muscle aching or cramping
• muscle pains or stiffness
• chest pressure or squeezing pain in chest
• excessive sweating
• feeling of heaviness, pain, warmth and/or swelling in a leg or in the pelvis
• sudden tingling or coldness in an arm or leg
• sudden slow or difficult speech
• sudden drowsiness or need to sleep
• fast breathing
• sharp pain when taking a deep breath
• fast or slow heartbeat
• coughing up blood
• rust colored urine
• decreased amount of urine

Data or information not available

References

1. ChemIDplus

   https://chem.nlm.nih.gov/chemidplus/sid/0105239916

   https://chem.nlm.nih.gov/chemidplus/sid/0114013513

   https://chem.sis.nlm.nih.gov/chemidplus/chemidheavy.jsp

2. EPA DSStox

   https://comptox.epa.gov/dashboard/dsstoxdb/results?search=DTXSID80147023

3. FDA/SPL Indexing Data

   https://www.fda.gov/ForIndustry/DataStandards/SubstanceRegistrationSystem-UniqueIngredientIdentifierUNII/

4. NCIt

   https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C9822

    

5. Wikipedia

   https://en.wikipedia.org/wiki/Cefclidin

6. PubChem

   https://pubchem.ncbi.nlm.nih.gov

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